NovaBone Putty®

NovaBone Putty is a versatile bone graft substitute that is ready to use out of the package with exceptional handling characteristics that will save time and improve placement.

The specially formulated consistency means it can be packed into any size or shape void without sticking to surgical gloves. The binder resists migration during irrigation allowing the bioactive component to stay as placed.

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Exceptional Handling Characteristics

Osteostimulative (2,3)
Highly malleable, easy to mold and pack into any defect
Stays at the surgical site, will not migrate during irrigation
Ready to use out of the package
Injectable into surgical site
Does not stick to surgical gloves

NovaBone is packaged in sterile thermoformed packs, as well as syringes for controlled delivery of bone graft.

A bioactive synthetic bone for faster healing

NovaBone® is a 100% bioactive synthetic material composed from elements that occur naturally in the body – silicon, sodium, calcium, phosphorus, and oxygen.
NovaBone is osteostimulative; defined as an accelerated bone formation process characterized by the active stimulation of osteoblast proliferation and differentiation due to cellular interaction with the ionic dissolution released during absorption.
NovaBone is a bioactive synthetic material capable of regenerating new bone from existing bone.
NovaBone demonstrated equivalent rates of bone growth when compared to autogenous bone graft.(1)
NovaBone causes genetic activation for osteoblast recruitment and proliferation.(2,3)
NovaBone is the optimum bone void filler, providing patients with reduced morbidity resulting from the harvesting of autograft.
NovaBone’s activating chemistry promotes bone formation and creates a scaffold for new bone growth.
NovaBone is a clinically proven bone growth catalyst.
NovaBone can be easily combined with autograft, allograft or autogenous growth factors to extend surgical options and promote accelerated healing.
NovaBone is available through MTF, the world’s largest tissue bank.

A timeline of bioactive healing

NovaBone initiates a surface chemical reaction immediately upon introduction to the surgical site.
Ions released from NovaBone stimulate osteoblasts and modify the material’s surface which attracts and binds the critical components for bone regeneration in the surgical site.
The ion release occurs continuously over time and is particularly critical in the initial weeks of healing. As the ion release progresses, the NovaBone material is transformed into an increasingly porous scaffold with a resulting increase in surface area. The ion release and surface modification combine to actually stimulate the osteoblasts involved in the repair process.

Proven bone formation

NovaBone Putty was shown to be substantially equivalent to NovaBone Particulate in a rabbit femoral condyle defect study. The critical sized femoral condyle model showed early bone formation at 6 weeks and mature bone at 12 weeks.

References

Brice Ilharreborde, MD, Etienne Morel, MD, Franck Fitoussi, MD, Ana Presedo, MD, Philippe Souchet, MD, Georges-François Penneçot, MD, and Keyvan Madza, MD. Bioactive Glass as a Bone Substitute for Spinal Fusion in Adolescent Idiopathic Scoliosis. J Pediatr Orthop. 2008; 28: 347-351.
Larry L. Hench, Julia M. Polak. A Genetic Basis for Design of Biomaterials for In Situ Tissue Regeneration. Key Engineering Materials 2008; 377: 151-166.
Larry L. Hench, David M. Gaisser, The Genetic Basis for Osteogenesis Stimulation by Controlled Release of Ionic Dissolution Products. Transactions of the Orthopedic Research Society, Annual Meeting, San Francisco, California, USA. March 2008: 1697.

Service

Service is essential to keep medical equipment operational and safe. Our Nordic service team consists of experienced service technicians stationed across the Nordic countries. Our service technicians are ready to take on your every service need.”